Nature Reviews
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Nature Reviews Microbiology: Type III secretion systems (T3SSs) are protein transport nanomachines that resemble molecular syringes and are found in numerous Gram-negative bacterial species. This Review summarizes our current understanding of the structure and function of these important protein secretion systems, incorporating new advances from cryo-electron microscopy and integrative imaging...
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Nature Reviews Microbiology Type III secretion systems T3SSs are protein transpo
Pamela Toubia
Juan David Salazar Ospina
Nature Reviews
Nature Reviews
04/21/2017 at 16:00. Facebook
Nature Reviews Gastroenterology and Hepatology: Lipid droplets (LDs) are dynamic organelles and many metabolic disorders results in abnormal lipid accumulation in the liver. This Review provides insights into LD biology and lipid homeostasis in the liver, as well as the role of LDs in liver diseases, including NAFLD, NASH and hepatitis C. [ Nature.com Link ] (£)
Nature Reviews Gastroenterology and Hepatology Lipid droplets LDs are dynamic or
Muhammad Zoabi
Nature Reviews
Nature Reviews
04/21/2017 at 15:00. Facebook
Cover competition - don’t miss your chance! Your image could be the cover of a Nature Reviews clinical journal. Follow the link for details on how to enter.
Cover competition dont miss your chance Your image could be the cover

Nature Reviews cover image competition!

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Rahila Mumtaz
Nature Reviews
Nature Reviews
04/21/2017 at 11:00. Facebook
Nature Reviews Cancer: Changes in the calcium signal enable cells to achieve specific outcomes. In this Review, Monteith et al. describe how the remodelling of the expression and activity of calcium channels and pumps in cancer cells can influence tumour progression. [ Nature.com Link ] (£)
Nature Reviews Cancer Changes in the calcium signal enable cells to achieve
Alonso Domínguez Alemán
Nature Reviews
Nature Reviews
04/20/2017 at 19:00. Facebook
Nature Reviews Cardiology: From a global perspective, the large and diverse African population is disproportionately affected by cardiovascular disease. In their Review, Keates et al. provide a contemporary overview of the cardiovascular risk profile of the African population by summarizing the historical pattern of cardiovascular disease in Africa. Currently free to access [ Nature.com Link ]
Nature Reviews Cardiology From a global perspective the large and diverse African
Francis Kirigin
Dana Al Habbal
Nature Reviews
Nature Reviews
04/20/2017 at 15:00. Facebook
This collection contains Reviews, commentaries and original research on the topic of diabetes, metabolism and the kidney, including the epidemiology and pathophysiology of diabetic nephropathy, the role of the kidney in glucose homeostasis, insulin resistance, and potential therapeutic targets for renal protection.
This collection contains Reviews commentaries and original research on the topic of

Diabetes, metabolism and the kidney

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Yennifer Lizeth Ignacion Leon
Gilson Pires Dorneles
Francisco Zanotelli Mattedi
Nature Reviews
Nature Reviews
04/20/2017 at 11:00. Facebook
Nature Reviews Neuroscience: Amyloid precursor protein (APP) has been heavily implicated in Alzheimer disease, but the physiological roles of APP and the related APP-like proteins (APLPs) remain less well understood. This Review examines the functions of the APP family and its fragments in CNS development, synaptic function, brain injury and ageing. [ Nature.com Link ] (£)
Nature Reviews Neuroscience Amyloid precursor protein APP has been heavily implicated in
Jenny Ekberg
Max Richter
Rogério Lima
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Nature Reviews
04/19/2017 at 19:00. Facebook
Nature Reviews Urology: The risk of urinary incontinence and other lower urinary tract (LUT) symptoms increases substantially with advancing age; however, such symptoms can emerge in otherwise healthy individuals. In this Review, the authors describe the changes in LUT physiology that take place during the ageing process, and whether or not these changes arise as a consequence of 'normal',...
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Nature Reviews Urology The risk of urinary incontinence and other lower urinary
Josue Rafael Bustos Montalvan
Nature Reviews
Nature Reviews
04/19/2017 at 16:00. Facebook
Nature Reviews Clinical Oncology: In less than a decade, the treatment landscape of metastatic melanoma has changed dramatically. Novel targeted agents and immunotherapies are revolutionizing patient outcomes, but the range of available drugs complicates clinical decision-making. Herein, the authors chart the therapeutic advances and review the current evidence that can be used to guide...
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Nature Reviews Clinical Oncology In less than a decade the treatment landscape
Christopher Skinner
Kaniska Mukherjee
Casey Borthwick
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Nature Reviews
04/18/2017 at 16:00. Facebook
Nature Reviews Endocrinology: Osteosarcoma typically occurs during the adolescent growth spurt and is the most common primary cancer of bone. Here, Sharon A. Savage and colleagues discuss how advances in germline and somatic genetics, tumour biology and animal models have enhanced our understanding of osteosarcoma aetiology and could lead to new therapeutic approaches to treat the disease. [...
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Nature Reviews Endocrinology Osteosarcoma typically occurs during the adolescent
Nature Reviews
Nature Reviews
04/18/2017 at 13:00. Facebook
Nature Reviews Neurology: Human induced pluripotent stem cells (hiPSCs) enable researchers to recapitulate an individual's neural development in a dish, with the potential to provide unique insight into the pathogenic mechanisms of neurodevelopmental disorders. Here, the authors provide an overview of disease modelling with hiPSCs and discuss existing hiPSC models of neurodevelopmental...
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Nature Reviews Neurology Human induced pluripotent stem cells hiPSCs enable researchers to
Samjhana Thapaliya
Kalpesh Ashara
Fabiana Bressan
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Nature Reviews
04/18/2017 at 12:04. Facebook
Springer Nature believes research is a global endeavor. Explore patterns of collaboration [ Nature.com Link ] #GlobalScience
Springer Nature believes research is a global endeavor Explore patterns of collaboration
Nature Reviews
Nature Reviews
04/18/2017 at 11:00. Facebook
Nature Reviews Immunology: Mitochondrial DNA (mtDNA) can engage multiple pattern-recognition receptors to trigger pro-inflammatory and type I interferon responses. This Review provides an overview of how these responses are activated by summarizing the unique features of mtDNA and how it is exposed during cellular stress. [ Nature.com Link ] (£)
Nature Reviews Immunology Mitochondrial DNA mtDNA can engage multiple patternrec
Filly Napolitano
Nature Reviews Disease Primers: Urothelial bladder cancer is one of the most common, and most deadly, malignant diseases worldwide. This Primer summarizes the current epidemiological and outcome data of patients with this disease, as well as describing how new molecular subtyping strategies might improve patient care in the future. [ Nature.com Link ]
Nature Reviews Disease Primers Urothelial bladder cancer is one of the most
Josue Rafael Bustos Montalvan
Nature Reviews Disease Primers: Bladder cancer is typically diagnosed cystoscopically after blood in the urine is detected. This PrimeView highlights some of the key facts of this common cancer. [ Nature.com Link ]
Nature Reviews Disease Primers Bladder cancer is typically diagnosed cystoscopic
Prachum Kumthaveewut
Nature Reviews Rheumatology: Components of the human diet can have a profound effect on the way in which the human body responds to its environment. In this Review, the authors discuss several common dietary factors, outlining their effects on the development and progression of autoimmune rheumatic diseases via a common factor — the microbiome. [ Nature.com Link ] (£)
Nature Reviews Rheumatology Components of the human diet can have a profound
Chien-Foung Huang
Paul Grijalva
Indhira Bisonó Jiménez
Nature Reviews Cardiology: Inflammatory processes have a crucial role in abdominal aortic aneurysm and aortic wall remodelling. This Review focuses on the involvement of monocytes and macrophages, summarizing current knowledge on their origin and the roles of distinct monocyte and macrophage subsets in AAA development and complications, and highlighting potential translational applications...
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Nature Reviews Cardiology Inflammatory processes have a crucial role in abdominal aortic
Marcus Vinícius
Ana Paula Brandalize
Nature Reviews Neuroscience: Lindenberger and colleagues suggest that research into the possible effects of 'brain training' should build on an understanding of the mechanisms of human brain plasticity. [ Nature.com Link ] (£)
Nature Reviews Neuroscience Lindenberger and colleagues suggest that research in
Guilherme Alves
Saulo Gil
Nature Reviews Gastroenterology and Hepatology: Gastrointestinal malignancies are among the most common human cancers. Genomic and transcriptomic analyses have identified recurring molecular subtypes that suggest important biological differences. Here, the authors review the common themes of gastrointestinal cancer subtypes, as well as how they could be implemented into clinical practice. [...
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Nature Reviews Gastroenterology and Hepatology Gastrointestinal malignancies are
Ricky Terminel Zaragoza
Lab Simone
Nature Reviews Molecular Cell Biology: Multiciliated cells line the lumen of the vertebrate central nervous system and respiratory and reproductive tracts, where the unidirectional beating of cilia assemblies supports the polarized flow of fluids or movement of cells or particles. Recent studies shed new light on how multiciliated cells arise and how they function. [ Nature.com Link ] (£)
Nature Reviews Molecular Cell Biology Multiciliated cells line the lumen of the