RefSeq Release 80 is now available on the FTP site, online and through NCBI’s E-utilities. For more details about RefSeq release 80, please see the latest story on NCBI News: [ Go.usa.gov Link ]

Please note that GI sequence identifiers will be removed from flat file and FASTA formats in the March 2017 RefSeq FTP release.

Also, RefSeq plans to start a comprehensive reannotation of all...
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RefSeq release 80 now available; GI identifiers to be removed in next...

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Two new videos on the NCBI YouTube channel demonstrate how to use Clone DB and clone placements to assess and improve genome assemblies.

Using Clone Placements to Interpret Genome Assemblies: [ Youtube.com Link ]

Clone DB FTP Files: Content and Uses for Genome Assemblies: [ Youtube.com Link ]

Subscribe to the NCBI YouTube channel to receive alerts about new videos ranging from quick tips to...
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Using Clone Placements to Interpret Genome Assemblies: 3 Examples

Learn how to use clone placement data from NCBI's Clone DB to interpret and improve genome assemblies.

YOUTUBE.COM
GenBank release 217.0 is now available via FTP. Head over to NCBI News to see stats for the update: [ Go.usa.gov Link ]

Data: [ 1.usa.gov Link ]

Release notes: [ 1.usa.gov Link ]

GenBank release 217.0 is available via FTP

go.usa.gov
Genome Workbench 2.11.7 is here! New features include a critical improvement in HTTPS protocol communication with NCBI, improved rendering for translation discrepancies, and improved handling of tracks. For a full list of changes, please see the Genome Workbench release notes [ Nlm.nih.gov Link ].
The newest video ([ Youtube.com Link ] on the NCBI YouTube channel is a brief introduction to a new set of sequence viewer renderings that better display discrepancies between genomic sequence and annotated features. These discrepancies can occur because RefSeq gene models based on the current genomic sequence can differ from RefSeq transcripts and corresponding proteins that come from our...
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Sequence Viewer: Display Translation Discrepancies

This is a brief introduction to a new set of sequence viewer renderings that better display discrepancies between genomic sequence and annotated...

YOUTUBE.COM
The newest video ([ Youtube.com Link ] on the NCBI YouTube channel is a brief introduction to a new set of sequence viewer renderings that better display discrepancies between genomic sequence and annotated features.

These discrepancies can occur because RefSeq gene models based on the current genomic sequence can differ from RefSeq transcripts and corresponding proteins that come from our...
View details ⇨

Sequence Viewer: Display Translation Discrepancies

This is a brief introduction to a new set of sequence viewer renderings that better display discrepancies between genomic sequence and annotated features. Th...

YOUTUBE.COM
The Consensus Coding Sequence (CCDS) update that compares NCBI's Mus musculus annotation release 106 to Ensembl's release 86 is now available in Gene. This update adds 938 new CCDS IDs, and adds 137 genes into the mouse CCDS set. CCDS release 21 includes a total of 25,757 CCDS IDs that correspond to 20,354 GeneIDs. [ Nlm.nih.gov Link ]

Also, note that the CCDS survey is still open. NCBI and...
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CCDS Report for Consensus CDS

ncbi.nlm.nih.gov
As you may have read in previous posts, NCBI is in the process of changing the way we handle GI numbers for sequence records. In short, we are moving to a time when accession.version identifiers, rather than GI numbers, will be the primary identifiers for sequence records. In a previous post, we outlined a method for converting GI numbers (used to identify sequence records) to...
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Converting Lots of GI Numbers to Accession.version

ncbiinsights.ncbi.nlm.nih.gov
Don’t forget to sign up for Wednesday’s #NCBIMinute, where we’ll show you how to bulk convert GIs -> acc.ver [ Gotowebinar.com Link ]
Next Wednesday, NCBI will demonstrate how to use a downloadable database and Python script to convert GI identifiers to accession.version. The file and service that will be used are suitable for one-time conversion of very large sets of data. Register here: [ Gotowebinar.com Link ]

NCBI Minute: Bulk Conversion of NCBI Sequence GI Identifiers to...

attendee.gotowebinar.com
Last Wednesday, ClinVar released over 138,000 variant interpretations submitted by Illumina Clinical Services Laboratory (ICSL) in San Diego, CA. This dataset represents a 57% increase in the number of submitted interpretations and makes ICSL the largest source of data in ClinVar. The contribution from ICSL also provides 78,590 novel variants to the database, an increase of 45% over the...
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Variant interpretations from Illumina double ClinVar data

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The new Human Genome Resources site offers access to visualization and analysis tools available for the human genome, as well as other relevant tools and databases. The resources are sorted into categories like Find, View, Download and Learn, making it easier to find what you need to complete tasks like:
• Finding information on individual genes that NCBI RefSeq staff annotate on the human...
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The new Human Genome Resources site: a portal for exploration of the...

go.usa.gov
Sequence Viewer 3.18 has several new features, improvements and bug fixes to the graphical viewer, including improved handling of translation discrepancies, a new option for “Left-to-right translations” for the six frame translation track, and improved code generation. For a full list of changes, see the Sequence Viewer release notes [ Nlm.nih.gov Link ].

Release Notes

ncbi.nlm.nih.gov
As you may have read in previous posts, NCBI is in the process of changing the way we handle GI numbers for sequence records. In short, we are moving to a time when accession.version identifiers, rather than GI numbers, will be the primary identifiers for sequence records. As part of this transition, an obvious question for any of you currently using GI numbers is how to convert a GI number to...
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Converting GI Numbers to Accession.version

ncbiinsights.ncbi.nlm.nih.gov
Application deadline for the January Hackathon at NIH is December 7th! Apply here: [ Goo.gl Link ]

Application for Participation in January 2017 Biomedical Informatics...

goo.gl
Will you be attending the American Society for Cell Biology 2016 National Meeting? If so, be sure to join us for a Tech Talk and at our booth (#939).

The Tech Talk, “Five Useful Teaching Examples Using NCBI BLAST”, is in Theater 2 on Sunday, Dec. 4 at 5:30 PM PDT. We will present demonstrations that highlight features of BLAST. More information on NCBI News: [ Go.usa.gov Link ]

We’ll be at...
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NCBI Tech Talk and Booth at the American Society for Cell Biology 2016...

go.usa.gov
Remember, applications for the January hackathon are due next Wednesday. Apply here: [ Goo.gl Link ]

Application for Participation in January 2017 Biomedical Informatics...

goo.gl
Evidence Viewer has been retired. For current evidence supporting annotated gene structures, see Gene. More information on NCBI News: [ Go.usa.gov Link ]

Evidence Viewer has been retired

go.usa.gov
Are you a student, postdoc, or investigator already engaged in using medical informatics data or pipelines for genomic analyses of next generation sequencing data?
Join us for a hackathon on the NIH campus: [ Goo.gl Link ]

Application for Participation in January 2017 Biomedical Informatics...

goo.gl
Are you a student, postdoc, or investigator already engaged in using medical informatics data or pipelines for genomic analyses of next generation sequencing data?

Join us for a hackathon on the NIH campus: [ Goo.gl Link ]

More info on NCBI News: [ Go.usa.gov Link ]

Application for Participation in January 2017 Biomedical Informatics...

goo.gl